Diagnosis. If your blood count is above 450,000 platelets per microliter of blood, your doctor will look for an underlying condition. He or she will rule out all other causes of high platelet counts to confirm a diagnosis of essential thrombocythemia .
A blood test for a specific gene, called JAK2, can diagnose thrombocytosis. However, it is positive in only about 50% of the cases. Other gene mutations are also tested, but are only positive in a low percentage of patients. The patient may have bone marrow removed and examined to help confirm the diagnosis.
Similarly, is thrombocytosis serious? Primary thrombocytosis, or essential thrombocythemia, can cause serious bleeding or clotting complications. These can usually be avoided by maintaining good control of the platelet count with medications. After many years, however, bone marrow fibrosis (scarring) can develop.
People with essential thrombocythemia might have signs and symptoms related to blood clots and bleeding, including:
A high platelet count can happen when something causes the bone marrow to make too many platelets. When the reason is unknown, it is called primary, or essential, thrombocytosis. When excess platelets are due to an infection or other condition, it is called secondary thrombocytosis.
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Essential thrombocythemia is an uncommon disorder in which your body produces too many blood platelets. This condition may cause you to feel fatigued and lightheaded and to experience headaches and vision changes. It also increases your risk of blood clots.
Treatment for this condition depends on the cause. If you've had significant blood loss from a recent surgery or an injury, your elevated platelet count might resolve on its own. If you have a chronic infection or an inflammatory disease, your platelet count likely will remain high until the condition is under control.
Platelet count increase significantly after strenuous type of exercise, but it is decrease after moderate type of exercise whereas very few number of study did not find any significant increase or decrease result of platelet count after doing exercise.
The most common reason for an elevated platelet count is reactive thrombocytosis. Recent studies have found that between 87% and 96% of people found to have platelet counts over 500, 000/?l had reactive thrombocytosis.
Normal platelet counts are in the range of 150, 000 to 400, 000 per microliter (or 150 - 400 x 109 per liter), but the normal range for the platelet count varies slightly among different laboratories. Mild to moderately elevated platelet counts are commonly seen when chronic inflammation is present.
Several vitamins and minerals can encourage a higher platelet count, including:Folate-rich foods. Share on Pinterest Black-eyed peas are a folate-rich food. Vitamin B-12-rich foods. Vitamin C-rich foods. Vitamin D-rich foods. Vitamin K-rich foods. Iron-rich foods.
Having a high platelet count is not always caused by cancer but it can be a reaction to a number of different health conditions, such as inflammatory disease and infection.
They suggested that reactive thrombocytosis is either mediated by high plasma levels of IL-6 or associated with high plasma levels of IL-6 in reaction to a common inflammatory process. Iron deficiency anemia is a cause of reactive thrombo- cytosis, and the thrombocytosis is usually mild to moderate degree.
Thrombocytosis is an adverse prognostic factor in many types of cancer. These include breast cancer, ovarian and other gynecologic cancers, renal cell carcinoma and lung cancers.
Stressful life events and anxiety usually cause an increase in platelet volume and activity through various mechanisms. RESULTS: MPV was found to be significantly higher (p = . 008) and platelet count was found to be significantly lower in the GAD group (p = . 001).
Dangerous internal bleeding can occur when your platelet count falls below 10, 000 platelets per microliter. Though rare, severe thrombocytopenia can cause bleeding into the brain, which can be fatal.
Causes of secondary thrombocytosis include infection, inflammatory states (for example, inflammatory bowel disease), physical stress (including the post-operative state), acute blood loss, iron deficiency anemia, post-splenectomy and underlying malignancy.
Lifestyle and home remediesEat healthy foods. Choose a varied diet rich in whole grains, vegetables and fruits, and low in saturated fats. Increase your physical activity. Aim for at least 30 minutes of moderate physical activity a day. Achieve or maintain normal weight. Stop smoking.
In general, a platelet count more than 450, 000 cells per microliter is considered elevated; this is known as thrombocytosis. There are numerous causes of thrombocytosis and fortunately, the majority are benign and transient. Let's will review some of the most common causes.
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